• CAS: 1159824-67-5
  • MDL:
  • Product number:QC-11782
  • Molecular formula: C15H17FN6O2S
  • Purity: 99.5%
  • MW: 364.4
Size Price Stock
100mg $495 in stock
250mg $850 in stock

Brief Description

CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
IC50 value: 1.0 uM
Target: PI 3Kγ
References on CZC24832:
[1]. Bell K, Sunose M, Ellard K, Cansfield A, Taylor J, Miller W, Ramsden N, Bergamini G, Neubauer G. SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors. oorg Med Chem Lett. 2012 Aug 15;22(16):5257-63.
[2]. Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Müller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957.


100 mM in DMSO

Melting point

Boiling point


Formula Weight:

Flash point

Storage conditions

Store at -20°C 2 years


White to off-white solid

All CEG Chemical products are intended for laboratory research use only.

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